Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mapk1  mitogen-activated protein kinase 1   (Synonyms: 9030612K14Rik, Erk2, MAPK2, p42mapk, Prkm1)
Results	Reference
1	J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26
1	J:112971 Camarero G, Tyrsin OY, Xiang C, Pfeiffer V, Pleiser S, Wiese S, Gotz R, Rapp UR, Cortical migration defects in mice expressing A-RAF from the B-RAF locus. Mol Cell Biol. 2006 Oct;26(19):7103-15
1	J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68
1	J:206944 Clegg JM, Conway CD, Howe KM, Price DJ, Mason JO, Turnbull JE, Basson MA, Pratt T, Heparan sulfotransferases Hs6st1 and Hs2st Keep Erk in check for mouse corpus callosum development. J Neurosci. 2014 Feb 5;34(6):2389-401
1	J:232897 Fremin C, Saba-El-Leil MK, Levesque K, Ang SL, Meloche S, Functional Redundancy of ERK1 and ERK2 MAP Kinases during Development. Cell Rep. 2015 Aug 11;12(6):913-21
1*	J:161097 Gauthier-Fisher A, Lin DC, Greeve M, Kaplan DR, Rottapel R, Miller FD, Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells. Nat Neurosci. 2009 Jun;12(6):735-44
1	J:242713 Ikeda Y, Zabbarova I, Schaefer CM, Bushnell D, De Groat WC, Kanai A, Bates CM, Fgfr2 is integral for bladder mesenchyme patterning and function. Am J Physiol Renal Physiol. 2017 Apr 01;312(4):F607-F618
1	J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66
1*	J:203480 Koyama N, Hayashi T, Mizukoshi K, Matsumoto T, Gresik EW, Kashimata M, Extracellular regulated kinase5 is expressed in fetal mouse submandibular glands and is phosphorylated in response to epidermal growth factor and other ligands of the ErbB family of receptors. Dev Growth Differ. 2012 Dec;54(9):801-8
1	J:238086 Kusano R, Fujita K, Shinoda Y, Nagaura Y, Kiyonari H, Abe T, Watanabe T, Matsui Y, Fukaya M, Sakagami H, Sato T, Funahashi JI, Ohnishi M, Tamura S, Kobayashi T, Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. FEBS Lett. 2016 Oct;590(20):3606-3615
1	J:310318 Li H, Tao C, Cai Z, Hertzler-Schaefer K, Collins TN, Wang F, Feng GS, Gotoh N, Zhang X, Frs2alpha and Shp2 signal independently of Gab to mediate FGF signaling in lens development. J Cell Sci. 2014 Feb 1;127(Pt 3):571-82
1	J:171515 Muller PS, Schulz R, Maretto S, Costello I, Srinivas S, Bikoff E, Robertson E, The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis. Development. 2011 Apr;138(7):1297-308
1	J:318016 Otani S, Kakinuma S, Kamiya A, Goto F, Kaneko S, Miyoshi M, Tsunoda T, Asano Y, Kawai-Kitahata F, Nitta S, Nakata T, Okamoto R, Itsui Y, Nakagawa M, Azuma S, Asahina Y, Yamaguchi T, Koshikawa N, Seiki M, Nakauchi H, Watanabe M, Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells. Biochem Biophys Res Commun. 2016 Jan 22;469(4):1062-8
1	J:158679 Pan Y, Carbe C, Powers A, Feng GS, Zhang X, Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development. Development. 2010 Apr;137(7):1085-93
1	J:246653 Park JC, Jeong WJ, Kim MY, Min D, Choi KY, Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development. J Cell Sci. 2016 Aug 01;129(15):2997-3007
1	J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088
1	J:137882 Samuels IS, Karlo JC, Faruzzi AN, Pickering K, Herrup K, Sweatt JD, Saitta SC, Landreth GE, Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function. J Neurosci. 2008 Jul 2;28(27):6983-95
1	J:186876 Sugiyama N, Tsukiyama T, Yamaguchi TP, Yokoyama T, The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice. Kidney Int. 2011 May;79(9):957-65
1*	J:168653 Sylvestersen KB, Herrera PL, Serup P, Rescan C, Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):105-11
1	J:225743 Um SH, Sticker-Jantscheff M, Chau GC, Vintersten K, Mueller M, Gangloff YG, Adams RH, Spetz JF, Elghazi L, Pfluger PT, Pende M, Bernal-Mizrachi E, Tauler A, Tschop MH, Thomas G, Kozma SC, S6K1 controls pancreatic beta cell size independently of intrauterine growth restriction. J Clin Invest. 2015 Jul 1;125(7):2736-47
1	J:99501 Wang J, Ito T, Udaka N, Okudela K, Yazawa T, Kitamura H, PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung. Tissue Cell. 2005 Feb;37(1):25-35
1	J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922
1	J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578
1	J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95
1	J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674